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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36369Generated: October 27, 2026

5-Bromopentanenitrile → 2,3-Dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)-1H-indole-3-pentanenitrile

https://huagongshe.com/reaction/36369

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromopentanenitrileHCID 79435—
Reactant2,3-dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)1H-indoleHCID 19438985—
Product2,3-Dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)-1H-indole-3-pentanenitrileHCID 1943898876%

Reaction Steps

By substituting 2,3-dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)1H-indole and 5-bromovaleronitrile in Example 1, the desired product was obtained in 76% yield as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05414004
Source datasetuspto-grants-1995_05
ORD IDord-8b7c9dcf4ce040aabd4e88121e025163
Source noteuspto-grants-1995_05