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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36370Generated: October 27, 2026

Ethyl 4-bromobutyrate → 2,3-Dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)-1H-indole-3-butanoic Acid Ethyl Ester

https://huagongshe.com/reaction/36370

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-bromobutyrateHCID 76300—
Reactant2,3-dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)1H-indoleHCID 19438985—
Product2,3-Dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)-1H-indole-3-butanoic Acid Ethyl EsterHCID 5374319980%

Reaction Steps

By substituting 2,3-dihydro-2-oxo-1-phenyl-3-(2-pyrazinylmethyl)-1H-indol and ethyl 4-bromobutyrate in Example 1, the desired product was obtained in 80% yield as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05414004
Source datasetuspto-grants-1995_05
ORD IDord-3c2bfaa231324b37b2a575ac9926683c
Source noteuspto-grants-1995_05