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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3638Generated: October 26, 2026

Morpholine → 1,3-Di-cyclopropylmethyl-8-morpholino Xanthine

https://huagongshe.com/reaction/3638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant1,3-Di-cyclopropylmethyl-8-chloroxanthineHCID 9814657—
Product1,3-Di-cyclopropylmethyl-8-morpholino XanthineHCID 9946149—

Reaction Steps

1,3-Di-cyclopropylmethyl-8-morpholino xanthine was prepared from 1,3-di-cyclopropylmethyl-8-chloroxanthine (0.3 g, 0.001 mol) and morpholine (0.2 g, 0.0022 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. >250° C., yield 0.09 g (26%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05734051
Source datasetuspto-grants-1998_03
ORD IDord-8724cdb4a4f141bd9d5804ebfdc64b3a
Source noteuspto-grants-1998_03