1-Mercapto-2-propanol → HCID 15295172, compound

HRID 363815

Reaction equation

HRID 363815 reaction equation
[N+:1]([C:4]1[CH:11]=[C:10]([NH2:12])[C:9](Cl)=[CH:8][C:5]=1[NH:6][CH3:7])([O-:3])=[O:2].[SH:14][CH2:15][CH:16]([OH:18])[CH3:17]>>[N+:1]([C:4]1[CH:11]=[C:10]([NH2:12])[C:9]([S:14][CH2:15][CH:16]([OH:18])[CH3:17])=[CH:8][C:5]=1[NH:6][CH3:7])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 1025451-Mercapto-2-propanolHCID 53793465HCID 53793465, compound

Product 1

HCID 15295172HCID 15295172, compoundYield 97.5%

Procedure

11.5 g (0.057 mol) of 2-nitro-4-amino-5-chloro-N-(methyl)aniline and 7.8 g (0.085 mol) of 1-mercaptopropan-2-ol were used as the starting materials to give dark brown crystals (14.3 g) melting at 152° C. (recrystallization from 96° ethanol) whose elemental analysis calculated for C10H15N3O3S was:

Sources & evidence

ORD record
ord-81abc15025a342188069438264b3853a
Source dataset
uspto-grants-1999_02
Patent number
US05874618

Linked notes

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