Ethylamine → 4-(Ethylamino)benzonitrile
Reaction equation
F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[CH2:10]([NH2:12])[CH3:11]>>[CH2:10]([NH:12][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1)[CH3:11]Participants
3
Procedure
According to a similar manner to that in Reference Example 1, the title compound was synthesized from 4-fluorobenzonitrile and 70% aqueous ethylamine solution.
Sources & evidence
- ORD record
- ord-c6332880f5504329a7d26ac369b34eb7
- Source dataset
- uspto-grants-2000_10
- Patent number
- US06127541
Reaction notes
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