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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 366449Generated: October 26, 2026

2-Bromo-1-(4-hydroxyphenyl)ethanone → 4-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromide

https://huagongshe.com/reaction/366449

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(4-hydroxyphenyl)ethanoneHCID 4964—
ReactantPyridine-2-carbothioamideHCID 1549499—
Reactant4-(2-Pyridin-2-yl-thiazol-4-yl)phenolHCID 23289260—
Product4-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromideHCID 23289259—

Reaction Steps

4-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromidewas preparedfrom α-bromo-4-hydroxyacetophenone and thiopicolinamide as described in Preparation 48; m.p. 261-262° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06130217
Source datasetuspto-grants-2000_10
ORD IDord-cb76f3756aba4075afde132627c20e3e
Source noteuspto-grants-2000_10