3-Nitrobenzylamine → 2,5-Dichloro-6-methyl 4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine
Reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH2:7][NH2:8])([O-:3])=[O:2].[Cl:12][C:13]1[N:14]=[C:15](Cl)[C:16]2[C:21]([Cl:22])=[C:20]([CH3:23])[S:19][C:17]=2[N:18]=1>>[Cl:12][C:13]1[N:14]=[C:15]([NH:8][CH2:7][C:6]2[CH:9]=[CH:10][CH:11]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[C:16]2[C:21]([Cl:22])=[C:20]([CH3:23])[S:19][C:17]=2[N:18]=1Participants
3
Procedure
Following the procedure of Example 1, the reaction of 3-nitrobenzylamine with 2,4,5-trichloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2,5-dichloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine
Sources & evidence
- ORD record
- ord-f4e3f3ee51704d97830dff32a84ad17f
- Source dataset
- uspto-grants-2000_10
- Patent number