1-Bromonaphthalene → 2-Chloro-n-ethyl-6-(1-naphthalenyl)benzamide

HRID 368589

Reaction equation

HRID 368589 reaction equation
[CH2:1]([NH:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2].Br[C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1>>[Cl:11][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]([C:22]2[C:23]3[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:19]=[CH:20][CH:21]=2)[C:5]=1[C:4]([NH:3][CH2:1][CH3:2])=[O:12]

Participants

3

Reactant 2

HCID 70011-BromonaphthaleneHCID 3479622-chloro-N-ethylbenzamide

Product 1

HCID 186301562-Chloro-n-ethyl-6-(1-naphthalenyl)benzamideYield 28%

Procedure

The title compound was prepared from the compound of Example f and 1-bromonaphthalene (0.76 g, 3.65 mmol) according to General Method D. It was obtained as 0.28 g of a white solid, a 28% yield. m.p. 181-182° C.

Sources & evidence

ORD record
ord-e949b9f27ca94845bbfe026088123e46
Source dataset
uspto-grants-2000_10
Patent number
US06133252

Linked notes

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