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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36951Generated: October 26, 2026

1-(2-Methoxyphenyl)piperazine → Methyl 3-[4-(4-o-methoxyphenylpiperazino)butyl]indole-5-carboxylate

https://huagongshe.com/reaction/36951

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methoxyphenyl)piperazineHCID 1346—
ReactantMethyl 3-(4-bromobutyl)indole-5-carboxylateHCID 19936440—
ProductMethyl 3-[4-(4-o-methoxyphenylpiperazino)butyl]indole-5-carboxylateHCID 19936434—

Reaction Steps

By reaction of methyl 3-(4-bromobutyl)indole-5-carboxylate with 1-(o-methoxyphenyl)piperazine "B" analogously to Example 1, methyl 3-[4-(4-o-methoxyphenylpiperazino)butyl]indole-5-carboxylate is obtained; hydrate, hydrochloride, m.p. 195°-196°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05418237
Source datasetuspto-grants-1995_05
ORD IDord-d6d39005fa2d48a18b5e64c86310db4f
Source noteuspto-grants-1995_05