N-Methylbenzamide → N-Methylbenzimidoyl chloride
Reaction equation
[CH3:1][NH:2][C:3](=O)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.S(Cl)([Cl:13])=O>>[CH3:1][N:2]=[C:3]([Cl:13])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1Participants
3
Procedure
N-Methyl benzamide (55.97 g., 418 mmole) and thionyl chloride (114.7 g, 0.96 mole) were treated as in Example I. Yield 58.4 g (91%) of the title compound, b.p. 80°-90° C. (~0.1 mm Hg).
Sources & evidence
- ORD record
- ord-a8c72cef2c564185b95a22d00e3d16a7
- Source dataset
- uspto-grants-1985_07
- Patent number
- US04528382
Reaction notes
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