7-Methylisatin → HCID 13519800, compound

HRID 371322

Reaction equation

HRID 371322 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2=[O:12].[Br:13]Br>ClC(Cl)C>[Br:13][CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2=[O:12]

Participants

4

Reactant 2

HCID 143137-MethylisatinHCID 24408Bromine

Product 1

HCID 13519800HCID 13519800, compound

Reagents, catalysts & solvents 1

HCID 63651,1-DichloroethaneSolvent

Procedure

The 7-methylisatin (16.1 g, 0.1 mole) is suspended in dichloroethane (2000 ml) and the suspension is heated and irradiated with a high intensity light source to the reflux point. Bromine (24.3 g, 0.15 mole) is added dropwise over a one hour period.

Workup

  1. temperaturethe suspension is heated
  2. customirradiated with a high intensity light source to the reflux point

Sources & evidence

ORD record
ord-ff59d6552f17494db82c24337df43ee5
Source dataset
uspto-grants-1985_07
Patent number
US04530929

Linked notes

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