Nitric Acid → HCID 13489933, compound
Reaction equation
[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]([F:12])([F:11])[F:10].[N+:13]([O-])([OH:15])=[O:14]>>[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([N+:13]([O-:15])=[O:14])=[CH:4][C:3]=1[C:9]([F:10])([F:11])[F:12]Participants
3
Procedure
72 gms of the crude mixture of 2, 4, and 6 mono chloro 3-methyl benzotrifluoride (0.37 moles) from Example I was added dropwise to 200 gms of 98% HNO3 at about -5° C. to 0° C. over a period of about 1 hour. After addition, solution was stirred for an additional 20 minutes. The solution was then washed with ice water and solvent extracted with CH2Cl2 to give 87 gms of an amber colored liquid. The liquid was distilled at 100°-110° C./(<0.1 mm) to give 84.5 gms of a yellow colored liquid (96% yield)
Workup
- additionAfter addition, solution
- washThe solution was then washed with ice water and solvent
- extractionextracted with CH2Cl2