3-Phenoxy-alpha-ethynylbenzylalcohol → 2,2-Dimethylspiro[2,4]heptane-1-carboxylic acid, alpha-ethynyl-m-phenoxybenzyl ester

HRID 371704

Reaction equation

HRID 371704 reaction equation
[CH3:1][C:2]1([CH3:12])[C:4]2([CH2:8][CH2:7][CH2:6][CH2:5]2)[CH:3]1[C:9]([OH:11])=[O:10].[C:13]([CH:15](O)[C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([O:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:17]=1)#[CH:14]>>[CH3:1][C:2]1([CH3:12])[C:4]2([CH2:8][CH2:7][CH2:6][CH2:5]2)[CH:3]1[C:9]([O:11][CH:15]([C:13]#[CH:14])[C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([O:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:17]=1)=[O:10]

Participants

3

Reactant 2

HCID 129190923-Phenoxy-alpha-ethynylbenzylalcoholHCID 20531773HCID 20531773, compound

Product 1

HCID 867335522,2-Dimethylspiro[2,4]heptane-1-carboxylic acid, alpha-ethynyl-m-phenoxybenzyl ester

Procedure

The procedure of Example 1 is followed using 2,2-dimethylspiro[2,4]heptane-1-carboxylic acid in place of 2,2-dimethyl-4,5-benzospiro[2,4]hepta-4,6-diene-1-carboxylic acid and α-ethynyl-m-phenoxybenzyl alcohol in place of m-phenoxybenzyl alcohol to give the product as an oil.

Sources & evidence

ORD record
ord-43eb503080ca45e19e009443edc74e75
Source dataset
uspto-grants-1978_05
Patent number
US04087523

Linked notes

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