HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Gabapentin | HCID 3446 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | Ethyl 2-[1-(aminomethyl)cyclohexyl]acetate | HCID 15512485 | — |
Reaction Steps
10 g. of the 1-aminomethyl-1-cyclohexane-acetic acid, prepared according to Example 1, are dissolved in 50 ml. anhydrous ethanol and saturated at 0° C. with gaseous hydrogen chloride. The reaction mixture is left to stand overnight at ambient temperature, then evaporated in a vacuum and the residue recrystallised from ethanol/ether. Ethyl 1-aminomethyl-1-cyclohexane-acetate is obtained in the form of its hydrochloride; m.p. 161° - 163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087544 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-405a81cc00a14ab4b6003f57296c8be8 |
| Source note | uspto-grants-1978_05 |