HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimetazidine → 7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-2,3-dihydro-1,4-benzodioxin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimetazidine | HCID 21109 | — |
| Reactant | 7-Hydroxy-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid | HCID 10899551 | — |
| Product | 7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-2,3-dihydro-1,4-benzodioxin | HCID 11102312 | 65% |
Reaction Steps
That compound is obtained in a yield of 65% starting from 1-(2,3,4-trimethoxy benzyl)piperazine and 7-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05420132 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-e2d3a32352c3451a856d603947c115da |
| Source note | uspto-grants-1995_05 |