2-Pyridineethanamine → HCID 178512782, compound

HRID 372013

Reaction equation

HRID 372013 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1.[S:10]([O-:14])([O-:13])(=[O:12])=[O:11].CS[C:17]([NH2:19])=[NH2+:18].CSC(N)=[NH2+]>O>[S:10]([OH:14])([OH:13])(=[O:12])=[O:11].[N:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[CH2:3][CH2:2][NH:1][C:17]([NH2:19])=[NH:18]

Participants

4

Reactant 2

HCID 759192-PyridineethanamineHCID 6604939S-methyl isothiourea hemisulfate

Product 1

HCID 178512782HCID 178512782, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2-(2-aminoethyl)pyridine (10.0 g) and S-methylthiouronium sulphate (11.39 g) in water (30 ml) is heated under reflux for two hours. The crude material, isolated in a manner similar to that described in Example 1, is recrystallized from water, yielding 2-(2-pyridyl)ethylguanidine sulphate, m.p. 264°-266° C.

Workup

  1. temperatureunder reflux for two hours
  2. customThe crude material, isolated in a manner similar to
  3. customis recrystallized from water

Sources & evidence

ORD record
ord-be4b542052714c54b65c5ae8e4689377
Source dataset
uspto-grants-1978_05
Patent number
US04088769

Linked notes

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