Acetic Anhydride → HCID 12803438, compound

Reaction equation

[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([C:17](=[O:19])[CH3:18])[C:6]1=[O:16]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 12803422HCID 12803422, compound

Product 1

HCID 12803438HCID 12803438, compound

Procedure

Approximately 21.8 g of 1-(2-methoxyethyl)-4-phenyl-4-imidazolin-2-one and 120 ml. of acetic anhydride is refluxed together for four hours. The acetic anhydride is distilled out at reduced pressure. The residual semisolid is recrystallized from ether to yield the title compound as a white solid; m.p. 73°-75° C.

Workup

distillationThe acetic anhydride is distilled out at reduced pressure
customThe residual semisolid is recrystallized from ether

Sources & evidence

ORD record: ord-ac67e13fd66845f781201b1fbf8d6d76
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04090025

Reaction notes

Loading…