Reaction equation
[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:14]([O-])([OH:16])=[O:15]>>[N+:14]([C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])=[O:8])([O-:16])=[O:15]Participants
3
Procedure
22 g of finely powdered 3-benzoylacrylic acid was added in 1-gram portions to 11° g of stirred fuming (90%) nitric acid at -5° over a 30-minute period, the mixture being allowed to heat to 0°. Then the temperature of the mixture was allowed to rise to 2° and held until a clear solution was obtained. The mixture then was poured on ice, and the solid which formed was filtered, washed with water, dried (MgS04) and recrystallized from ethanol to give 3-(3-nitrobenzoyl)acrylic acid (8A), m.p.: 199°-201°.
Workup
- temperatureto heat to 0°
- customto rise to 2°
- customwas obtained
- additionThe mixture then was poured on ice
- customthe solid which formed
- filtrationwas filtered
- washwashed with water
- customdried (MgS04)
- customrecrystallized from ethanol
Sources & evidence
- ORD record
- ord-10352e81e93d4dd79a04958ae164118c
- Source dataset
- uspto-grants-1978_05
- Patent number
- US04091221
Linked notes
Loading…