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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 373548Generated: October 27, 2026

Gamma-Butyrolactone → 8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepine

https://huagongshe.com/reaction/373548

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGamma-ButyrolactoneHCID 7302—
Reactant3-BromophenolHCID 11563—
Product8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepineHCID 19935534—

Reaction Steps

m-Bromophenol was reacted with γ-butyrolactone in analogy to Example 17, paragraphs B, C and D, to give 8-bromo-2,3,4,5-tetrahydro-1-benzoxepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05164387
Source datasetuspto-grants-1992_11
ORD IDord-53b5d9b21b7644e081b762608c11413b
Source noteuspto-grants-1992_11