Ethyl isothiocyanate → BM 20

Reaction equation

[CH:1]1([NH:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][C:11]=2[S:16]([NH2:19])(=[O:18])=[O:17])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:20]([N:22]=[C:23]=[S:24])[CH3:21]>>[CH:1]1([NH:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][C:11]=2[S:16]([NH:19][C:23]([NH:22][CH2:20][CH3:21])=[S:24])(=[O:18])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1

Participants

Reactant 2

HCID 10966Ethyl isothiocyanate

HCID 151356184-(Cyclooctylamino)pyridine-3-sulfonamide

Product 1

HCID 3025730BM 20

Procedure

The procedure is identical to that of Example 5, using (4-(cyclooctylamino)pyrid-3-yl)sulfonamide and ethylisothiocyanate as the starting materials. Yield is similar. Melting point: 196°-198° C.

Workup

customYield

Sources & evidence

ORD record: ord-89da2abf0df74de5aae2ff3dab5be48e
Source dataset: uspto-grants-1992_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05166162

Reaction notes

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