HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | Ethyl 2-(4-nitro-1H-imidazole-1-yl)octanoate | HCID 10062368 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide | HCID 15222339 | — |
Reaction Steps
Ethyl 2-(4-nitro-1H-imidazol-1-yl)octanoate (17 moles, 5.0 g) and ethylamine (20 ml) were stirred in 150 ml ethanol at room temperature for 16 hours. The reaction was added to ice water, extracted with ethyl acetate, washed with water, dried over sodium sulfate and concentrated. The oil crystallized upon standing to yield 3.9 g of N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide. (MS).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484780 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-fd4c582d41ef494f8ba2e0064e6fd39f |
| Source note | uspto-grants-1996_01 |