HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethoxycinnamic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,3-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethoxycinnamic acid | HCID 99525 | — |
| Reactant | 5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione | HCID 5098605 | — |
| Product | 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,3-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)- | HCID 6448784 | 36% |
Reaction Steps
Substantially the same procedure as in Reference Example 1 was repeated using 2.0 g (8.85 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.2 g (10.6 mmol) of 2, 3-dimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from chloroform/cyclohexane to give 1.26 g (yield 36%) of Compound 28 as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484920 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-02c5d58afb66443684f4c024284fa1ff |
| Source note | uspto-grants-1996_01 |