1H-Indene, 2-methyl- → HCID 178506826, compound

HRID 375650

Reaction equation

HRID 375650 reaction equation
[CH3:1][C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.C([Li:15])CCC>CCOCC>[CH3:1][C:2]1[CH:10]([Li:15])[C:9]2[C:4]([CH:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2

Participants

4

Reactant 2

HCID 165871H-Indene, 2-methyl-HCID 178418339Butyllithium

Product 1

HCID 178506826HCID 178506826, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2-methylindene (47.2 g) was dissolved in ether (400 ml) and n-butyl lithium (145.2 ml, 2.5M in Hexane) was added dropwise over 3 hours. The mixture was stirred for 2.5 hours. After evaporation of the solvent, the residual solid was washed twice with n-pentane (400 ml). Drying under vacuum gave 2-methylindenyl lithium (42 g, 85%) as a pale brown powder.

Workup

  1. customAfter evaporation of the solvent
  2. washthe residual solid was washed twice with n-pentane (400 ml)
  3. customDrying under vacuum

Sources & evidence

ORD record
ord-0f86d650d0844e50a064af3974b0e352
Source dataset
uspto-grants-1996_01
Patent number
US05486585

Linked notes

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