2,3-Dichloro-1,1,1,4,4,4-hexafluorobut-2-ene → 2-(1-Chloro-2,2,2-trifluoroethyl)-2-trifluoromethyl-[1,3]-dioxolo[4,5-b]pyridine

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Reaction Steps

11 g of 2,3-dihydroxypyridine were reacted with 23.5 g of 2,3-dichloro-1,1,1,4,4,4-hexafluorobut-2-ene as described in Example 2. After distillation under high vacuum, the product was obtained in an amount of 15.5 g (=50% of theory) in the form of colourless crystals. The NMR spectra showed the following characteristic absorptions: 19F NMR: -68.5 and -81.6 ppm. 1H NMR: 4.81 ppm.

Provenance & Evidence