Formaldehyde → HCID 18991206, compound
Reaction equation
[C:1]([C:5]1[CH:6]=[C:7](Br)[CH:8]=[C:9]([C:16]([CH3:19])([CH3:18])[CH3:17])[C:10]=1[O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])([CH3:4])([CH3:3])[CH3:2].[CH2:21]=[O:22]>>[C:1]([C:5]1[CH:6]=[C:7]([CH:8]=[C:9]([C:16]([CH3:19])([CH3:18])[CH3:17])[C:10]=1[O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[CH:21]=[O:22])([CH3:4])([CH3:3])[CH3:2]Participants
3
Procedure
By proceeding as indicated in the procedure of Preparation VII above, starting with 10 mmol of 3,5-di-t-butyl-4-trimethylsilyloxy-bromobenzene and 15 mmol of HCHO (in the protected form of H2C(OCH3)2), one obtains (yield: 45%) 3,5-di-t-butyl-4-trimethylsilyloxy-benzaldehyde, followed by the expected product, 3,5-di-t-butyl-4-hydroxybenzaldehyde.
Sources & evidence
- ORD record
- ord-af45e39ef51a45c29ee659f8040b5eec
- Source dataset
- uspto-grants-1996_01