2-Iodophenol → 3-(2-Chloro-6-iodophenoxy)cyclopentene

HRID 37606

Reaction equation

HRID 37606 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([I:16])[C:11]=1[OH:17].[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([OH:25])=[C:21]([I:26])[CH:20]=1>>[I:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][CH:12]1[CH2:13][CH2:14][CH:15]=[CH:10]1.[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([I:16])[C:11]=1[O:17][CH:21]1[CH2:22][CH2:23][CH:24]=[CH:19]1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([O:25][CH:4]2[CH2:5][CH2:6][CH:7]=[CH:2]2)=[C:21]([I:26])[CH:20]=1

Participants

6

Reactant 3

HCID 107842-IodophenolHCID 6202344-Chloro-2-iodophenolHCID 114708202-Chloro-6-iodophenol

Product 3

HCID 199359043-(2-Chloro-6-iodophenoxy)cyclopenteneHCID 199359223-(4-Chloro-2-iodophenoxy)cyclopenteneHCID 199359253-(2-Iodophenoxy)cyclopentene

Procedure

The same procedure as in Comparative Example 2 except that 2-iodophenol, 2-chloro-6-iodophenol or 4-chloro-2-iodophenol is employed in place of 2,4-dichloro-6-iodophenol yields 3-(2-iodophenoxy)cyclopentene, 3-(2-chloro-6-iodophenoxy)cyclopentene or 3-(4-chloro-2-iodophenoxy)cyclopentene, respectively.

Sources & evidence

ORD record
ord-4465ef8bdb0c4ddda826944ee1ffa6aa
Source dataset
uspto-grants-1995_05
Patent number
US05420310

Linked notes

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