Benzyl Alcohol → 1-(2-Bromophenyl)ethanol

HRID 376831

Reaction equation

C(O)C1C=CC=CC=1.C1([Sn](C2CCCCC2)(C2CCCCC2)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[CH:22]([OH:24])[CH3:23])CCCCC1.[Br:37]C1C=CC=CC=1CO>>[Br:37][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[CH:22]([OH:24])[CH3:23]

Participants

Reactant 3

HCID 244Benzyl Alcohol

HCID 728502-Bromobenzyl alcohol

HCID 19359512Tricyclohexyl [o-(1-hydroxyethyl)phenyl]tin

Product 1

HCID 954551-(2-Bromophenyl)ethanolYield 75.1%

Procedure

17.2 g of o-[tri(cyclohexyl)]tin]benzylalcohol was obtained in the same manner as in the synthesis of tricyclohexyl[o-(1-hydroxyethyl)phenyl]tin of Example 1-(4), with the exception that 9.40 g of o-bromobenzylalcohol (50.2 mmol), prepared in the aforementioned example (1), instead of o-bromo-1-phenyl ethanol (yield=75.1%).

Sources & evidence

ORD record: ord-3367da7ec83a4b569278ddffb8d8c220
Source dataset: uspto-grants-2000_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06022822

Linked notes

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