3-Pyrrolidone, 1-methyl- → HCID 70249731, compound

HRID 376834

Reaction equation

HRID 376834 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:7][C:8]1[CH:12]=[C:11]([CH:13]=[C:14]2[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15]2)[O:10][N:9]=1.[CH3:20]N1CCC(=O)C1.CC1C=C(C[Si](C)(C)C)ON=1>>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:7][C:8]1[CH:12]=[C:11]([CH:13]=[C:14]2[CH2:18][CH2:17][CH2:20][N:16]([CH3:19])[CH2:15]2)[O:10][N:9]=1

Participants

4

Reactant 3

HCID 1442833-Pyrrolidone, 1-methyl-HCID 10986681Isoxazole, 3-methyl-5-[(trimethylsilyl)methyl]-HCID 70087037HCID 70087037, compound2×

Product 1

HCID 70249731HCID 70249731, compound

Procedure

3-(3-methyl-5-isoxazolyl)methylene-1-methylpyrolidine oxalate, compound 8, and (E) 3-(3-methyl-5-isoxazolyl)methylene-1-methylpyrrolidine oxalate, compound 9, starting form 1-methyl-pyrrolidin-3-one (J. Amer. Chem. Soc., 55, 1933, 1233-1241) and 3-methyl-5-trimethylsilylmethyl-isoxazole.

Sources & evidence

ORD record
ord-48109cd8a4e949bdb140a50f345e55d4
Source dataset
uspto-grants-2000_02
Patent number
US06022868

Linked notes

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