3-Amino-1-phenylpropan-1-ol → (3-Hydroxy-3-phenylpropyl)-carbamic acid ethyl ester

HRID 377464

Reaction equation

HRID 377464 reaction equation
[NH2:1][CH2:2][CH2:3][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5].Cl[C:13]([O-])=O.[C:16]([O:19][C:20]([O-])=O)([O-])=[O:17]>>[OH:5][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][CH2:2][NH:1][C:16]([O:19][CH2:20][CH3:13])=[O:17]

Participants

4

Reactant 3

HCID 1215483-Amino-1-phenylpropan-1-olHCID 15238643PyrocarbonateHCID 21226386Carbonochloridate

Product 1

HCID 19358983(3-Hydroxy-3-phenylpropyl)-carbamic acid ethyl ester

Procedure

reacting said α-(2-aminoethyl)benzenemethanol with a chloroformate or dicarbonate to form an N-(3-hydroxy-3-phenylpropyl)urethane;

Sources & evidence

ORD record
ord-4246380a9937461c96540c7865753554
Source dataset
uspto-grants-2000_02
Patent number
US06025517

Linked notes

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