Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379896Generated: October 27, 2026

(1S)-2-Chloro-1-methyl-2-oxoethyl acetate → 3-[[(S)-2-Acetoxypropionyl]amino]-6-chloro-2-(4-methylpyridine-2-carbonyl)indole

https://huagongshe.com/reaction/379896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-2-Chloro-1-methyl-2-oxoethyl acetateHCID 11094804—
Reactant3-Amino-6-chloro-2-(4-methylpyridine-2-carbonyl)indoleHCID 18368098—
Product3-[[(S)-2-Acetoxypropionyl]amino]-6-chloro-2-(4-methylpyridine-2-carbonyl)indoleHCID 53721598—

Reaction Steps

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(4-methylpyridine-2-carbonyl)indole (Example 70) and (S)-(−)-2-acetoxypropionyl chloride. m.p.: 213-214° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06300363B1
Source datasetuspto-grants-2001_10
ORD IDord-86d31a9ec1d14e3a82c59d075181c4f9
Source noteuspto-grants-2001_10