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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 38264Generated: October 26, 2026

Phenylmethanesulfonyl chloride → [4-Chloro-2-[4-[(phenylmethyl)sulfonyl]-1-piperazinyl]phenoxy]-acetic acid

https://huagongshe.com/reaction/38264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethanesulfonyl chlorideHCID 74740—
Reactant[4-chloro-2-(1-piperazinyl)phenoxy]-acetic Acid, Ethyl Ester Hydrochloride SaltHCID 86631058—
Product[4-Chloro-2-[4-[(phenylmethyl)sulfonyl]-1-piperazinyl]phenoxy]-acetic acidHCID 11568054—

Reaction Steps

Prepared from the product from Example 38 step c) and benzenemethanesulfonyl chloride according to the procedure described in Example 38 step d) to give the sub-title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524715B2
Source datasetuspto-grants-2013_09
ORD IDord-92c4883201fb4ee6b1ddd377316c0e3f
Source noteuspto-grants-2013_09