Benzenesulfonyl chloride → [4-Chloro-2-[[3-methyl-4-(phenylsulfonyl)-1-piperazinyl]methyl]phenoxy]acetic Acid
Reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([CH2:13][N:14]2[CH2:19][CH2:18][N:17]([S:20]([CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26]C=3)(=[O:22])=[O:21])[CH:16]([CH3:30])[CH2:15]2)[CH:3]=1.C1(S(Cl)(=O)=O)C=CC=CC=1>>[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([CH2:13][N:14]2[CH2:19][CH2:18][N:17]([S:20]([C:23]3[CH:26]=[CH:27][CH:28]=[CH:29][CH:24]=3)(=[O:21])=[O:22])[CH:16]([CH3:30])[CH2:15]2)[CH:3]=1Participants
3
Procedure
Prepared by the method of example 30, using the product from example 56 part (a) and is benzenesulfonyl chloride to give the title compound.
Workup
- customPrepared by the method of example 30