4-(2-Chloro-ethanesulfonyl)-phenol → HCID 10134061, compound

HRID 382783

Reaction equation

HRID 382783 reaction equation
Cl[CH2:2][CH2:3][S:4]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)(=[O:6])=[O:5].[CH2:14]([C@@H:21]1[CH2:26][CH2:25][NH:24][CH2:23][C@@H:22]1[OH:27])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([C@@H:21]1[CH2:26][CH2:25][N:24]([CH2:2][CH2:3][S:4]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)(=[O:6])=[O:5])[CH2:23][C@@H:22]1[OH:27])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 98132494-(2-Chloro-ethanesulfonyl)-phenolHCID 53778456HCID 53778456, compound

Product 1

HCID 10134061HCID 10134061, compoundYield 50%

Procedure

The title compound was prepared from 4-(2-chloro-ethanesulfonyl)-phenol and (3R,4R)-4-benzyl-piperidine-3-ol in 50% yield as a white solid.

Sources & evidence

ORD record
ord-95590d48cbc144239df6ad404f44df91
Source dataset
uspto-grants-2001_10
Patent number
US06310213B1

Linked notes

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