3-Chloro-4-(3-fluorobenzyloxy)aniline → tert-Butyl 4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Participants

Reaction Steps

In analogy to Example 54A, the title compound was synthesized from 3-chloro-4-[(3-fluorobenzyl)oxy]aniline from Example 4A (180 mg, 0.72 mmol) and tert-butyl 4-chloro-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c′]dipyridine-7(6H)-carboxylate (250 mg, 0.72 mmol) from Example 53A to yield 258 mg (64%).

Provenance & Evidence