4,5-Pyrimidinediamine, 6-chloro- → 6-Chloro-8-(2,4-dimethoxy-5-bromo-phenyl)-purine

HRID 3882

Reaction equation

HRID 3882 reaction equation
[NH2:1][C:2]1[C:7]([NH2:8])=[C:6]([Cl:9])[N:5]=[CH:4][N:3]=1.[CH3:10][O:11][C:12]1[CH:20]=[C:19]([O:21][CH3:22])[C:18]([Br:23])=[CH:17][C:13]=1[C:14](O)=O>>[Cl:9][C:6]1[N:5]=[CH:4][N:3]=[C:2]2[C:7]=1[NH:8][C:14]([C:13]1[CH:17]=[C:18]([Br:23])[C:19]([O:21][CH3:22])=[CH:20][C:12]=1[O:11][CH3:10])=[N:1]2

Participants

3

Reactant 2

HCID 780104,5-Pyrimidinediamine, 6-chloro-HCID 135050975-Bromo-2,4-dimethoxybenzoic acid

Product 1

HCID 201532746-Chloro-8-(2,4-dimethoxy-5-bromo-phenyl)-purine

Procedure

Prepared analogously to Example 14 from 4,5-diamino-6-chloropyrimidine and 2,4-dimethoxy-5-bromo-benzoic acid.

Sources & evidence

ORD record
ord-812dd49b20de4a6eb087670e6fda7435
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Linked notes

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