Chloramphenicol → 3-Hydroxybutyrate 4-hydroxybutyrate lactate

HRID 389839

Reaction equation

[OH:1][CH2:2][CH2:3][CH2:4][C:5]([O-:7])=[O:6].[OH:8][CH:9]([CH3:14])[CH2:10][C:11]([O-:13])=[O:12].C[C:16]1(C)S[C@@H]2[C@H](NC([C@H](N)C3C=CC=CC=3)=O)C(=O)N2[C@H:17]1[C:35]([OH:37])=[O:36].C1C([C@@H](O)[C@H](NC(C(Cl)Cl)=O)C[OH:48])=CC=C([N+]([O-])=O)C=1>>[OH:8][CH:9]([CH3:14])[CH2:10][C:11]([O-:13])=[O:12].[OH:1][CH2:2][CH2:3][CH2:4][C:5]([O-:7])=[O:6].[C:35]([O-:37])(=[O:36])[CH:17]([CH3:16])[OH:48]

Participants

Reactant 4

HCID 5959Chloramphenicol2×

HCID 6249Ampicillin2×

HCID 30370324-Hydroxybutanoate2×

HCID 35411123-Hydroxybutyrate

Product 1

HCID 866450883-Hydroxybutyrate 4-hydroxybutyrate lactate

Procedure

3-Hydroxybutyrate-4-hydroxybutyrate-lactate terpolymer was prepared according to the method of example 2 except that the collected cells was anaerobically cultured for 3 days in MR medium further containing 2 g/L of 4-hydroxybutyrate (4-HB), 1 g/L of 3-hydroxybutyrate (3-HB), 100 mg/L of ampicillin and 30 mg/L of chloramphenicol instead of MR medium further containing g/L of 4-HB, 100 mg/L of ampicillin and 30 mg/L of chloramphenicol.

Sources & evidence

ORD record: ord-916d5396b09e4b739a37a428a6b3c3a7
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08383379B2

Linked notes

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