Methyl iodide → Quinolinium, 1-methyl-, iodide (1:1)
Reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH3:11][I:12]>O1CCOCC1>[I-:12].[CH3:11][N+:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 150 °C
Procedure
N-methylquinolinium iodide (Compound III) was synthesized according to the description in the aforementioned reference. Specifically, 2.4 mL of quinoline and 4 mL of methyl iodide were added to 42 mL of anhydrous dioxane, which was stirred at 150° C. for one hour. Thereafter, it was filtered and thereby a precipitate was collected and then washed with ether and petroleum ether. This was dried and thus N-methylquinolinium iodide (Compound III) was obtained.
Workup
- customN-methylquinolinium iodide (Compound III) was synthesized
- filtrationThereafter, it was filtered
- customa precipitate was collected
- washwashed with ether and petroleum ether
- customThis was dried
Sources & evidence
- ORD record
- ord-6af5ef6efe2a4092938a0c01e49a2c54
- Source dataset
- uspto-grants-2013_02
- Patent number
- US08383792B2
Reaction notes
Loading…