HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-iodo-1H-imidazole → (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-iodo-1H-imidazole | HCID 606522 | — |
| Reactant | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| Product | (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24954181 | 46% |
Reaction Steps
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 5-iodo-1H-imidazole were reacted to give the title compound as a white foam (24 mg, 46%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383825B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-36407a5c78d0444593bbcec4ff21248d |
| Source note | uspto-grants-2013_02 |