HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Phe-Gly
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Fmoc-Phe-Gly-OH | HCID 11328236 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Phe-Gly | HCID 6992304 | — |
Reaction Steps
Fmoc-protected dipeptide 72 (500 mg, 1.00 mmol) was treated with a 5% v/v solution of piperidine in DMF (5 mL). After stirring for 1 h, the reaction mixture was concentrated to dryness. The crude material was used for the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524691B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-f2ae1b8090a940d2913985de4b8df854 |
| Source note | uspto-grants-2013_09 |