HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Glycyl-phenylalanyl-glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | N-Fmoc-glycyl-L-phenylalanyl-glycine | HCID 15222489 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Glycyl-phenylalanyl-glycine | HCID 6992441 | — |
Reaction Steps
Fmoc-protected tripeptide 74 (546 mg, 0.98 mmol) was treated with a 5% v/v solution of piperidine in DMF (5 mL). After stirring for 45 min, the reaction mixture was concentrated to dryness. The crude material was used for the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524691B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-7e66b13904154ebcbe524b75757fe2f1 |
| Source note | uspto-grants-2013_09 |