(3,5-dimethylpyrazol-1-yl)-(9H-xanthen-9-yl)methanone → 9H-Xanthene-9-carboxylic acid (5-cyclopropyl-[1,3,4]oxadiazol-2-yl)-amide

HRID 392732

Reaction equation

HRID 392732 reaction equation
CC1C=C(C)N([C:8]([CH:10]2[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[O:17][C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)=[O:9])N=1.[CH:24]1([C:27]2[O:31][C:30]([NH2:32])=[N:29][N:28]=2)[CH2:26][CH2:25]1>>[CH:24]1([C:27]2[O:31][C:30]([NH:32][C:8]([CH:10]3[C:23]4[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=4[O:17][C:16]4[C:11]3=[CH:12][CH:13]=[CH:14][CH:15]=4)=[O:9])=[N:29][N:28]=2)[CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 4521579(3,5-dimethylpyrazol-1-yl)-(9H-xanthen-9-yl)methanoneHCID 167677875-Cyclopropyl-1,3,4-oxadiazol-2-amine

Product 1

HCID 99495039H-Xanthene-9-carboxylic acid (5-cyclopropyl-[1,3,4]oxadiazol-2-yl)-amide

Procedure

The title compound, white solid, m.p. 246-248° C. and MS: m/e=333.1 (M+H+) was prepared in accordance with the general method of example 48a from (3,5-dimethylpyrazol-1-yl)-(9H-xanthen-9-yl)-methanone and 5-cyclopropyl-[1,3,4]oxadiazol-2-ylamine [J.Med.Pharm.Chem. 5, 617(1962)].

Sources & evidence

ORD record
ord-de91f304642c41d78a3d379fe7eca29f
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Linked notes

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