2-Methylbutanal → N-{6-({(3R)-1-(2-methylbutyl)-3-piperidyl}methyl)amino-6-oxohexyl)-3,3,3-triphenylpropanamide

HRID 394015Notes

Reaction equation

HRID 394015 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([CH2:7][NH:8][C:9](=[O:38])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH:15][C:16](=[O:37])[CH2:17][C:18]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:2]1.[CH3:39][CH:40]([CH2:43][CH3:44])[CH:41]=O>>[CH3:39][CH:40]([CH2:43][CH3:44])[CH2:41][N:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([CH2:7][NH:8][C:9](=[O:38])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH:15][C:16](=[O:37])[CH2:17][C:18]([C:31]2[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=2)([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:2]1

Participants

3

Reactant 2

HCID 72842-MethylbutanalHCID 11092454N-{6-{((3S)-3-piperidyl)methyl}amino-6-oxohexyl}-3,3,3-triphenylpropanamide

Product 1

HCID 69100899N-{6-({(3R)-1-(2-methylbutyl)-3-piperidyl}methyl)amino-6-oxohexyl)-3,3,3-triphenylpropanamide

Procedure

The title compound was prepared by a method similar to Step 3 of Example 17, using N-{6-{((3S)-3-piperidyl)methyl}amino-6-oxohexyl}-3,3,3-triphenylpropanamide and 2-methylbutanal. The compound was obtained as a white foamy substance.

Workup

  1. customThe compound was obtained as a white foamy substance

Sources & evidence

ORD record
ord-0af1b6ed4f3c4010b6e09a840ad2a690
Source dataset
uspto-grants-2004_10
Patent number
US06809108B1

Reaction notes

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