Formaldehyde → 2-Propyl-6-Methyldodecanoic Acid

Reaction equation

Br[CH:2]([CH2:4]CCCCC)[CH3:3].C[CH:11]([CH2:23][CH2:24]C)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([OH:22])=[O:21].C=O.[CH2:28](Br)CC>>[CH2:3]([CH:19]([CH2:18][CH2:17][CH2:16][CH:15]([CH3:28])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:23][CH3:24])[C:20]([OH:22])=[O:21])[CH2:2][CH3:4]

Participants

Reactant 4

HCID 712Formaldehyde

HCID 78401-Bromopropane

HCID 79046Sec-octyl bromide, (+-)-

HCID 2225183410-Methyltridecanoic Acid

Product 1

HCID 222518302-Propyl-6-Methyldodecanoic Acid

Procedure

The procedure used is that of GENERAL PROCEDURE III except that 2-bromooctane is used as compound (1) in step (a), formaldehyde is used in place of ethylene oxide in step (b), y=1, and propyl bromide is used in place of methyl iodide in step (h).

Sources & evidence

ORD record: ord-0fd3d43f752f45ffbe5d4694f158d06b
Source dataset: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06602845B2

Reaction notes

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