2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoyl fluoride → Sodium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate

HRID 3948

Reaction equation

HRID 3948 reaction equation
[F:1][C:2]([C:17]([F:20])([F:19])[F:18])([O:6][C:7]([F:16])([F:15])[C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10])[C:3](F)=[O:4].C[Si](C)(C)[O-:23].[Na+:26]>ClC1C=CC=CC=1Cl>[F:1][C:2]([C:17]([F:18])([F:19])[F:20])([O:6][C:7]([F:15])([F:16])[C:8]([F:13])([F:14])[C:9]([F:12])([F:10])[F:11])[C:3]([O-:4])=[O:23].[Na+:26]

Participants

4

Reactant 2

HCID 1027402,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoyl fluorideHCID 23672319Sodium trimethylsilanolate

Product 1

HCID 3765118Sodium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoateYield 77.3%

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Procedure

The procedure of Example 1 was followed using perfluoro-2-methyl-3-oxahexanoyl fluoride (16.6 g, 50 mmol), sodium trimethylsilanolate (5.6 g, 50 mmol), dry o-dichlorobenzene (200 mL), and 1 h at room temperature followed by rapid heating to 150°. Sodium perfluoro-2-methyl-3-oxahexanoate (13.6 g, 77% yield) was isolated as a white solid: The 19F NMR data were the same as reported in Example 15.

Workup

  1. customat room temperature
  2. temperatureby rapid heating to 150°

Sources & evidence

ORD record
ord-12ad0a1eb8d44e2fbf384c250faa7679
Source dataset
uspto-grants-1988_02
Patent number
US04723016

Linked notes

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