HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-o-toluidine → 3-[(2-Methyl-4-iodophenyl)amino]isonicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-o-toluidine | HCID 83221 | — |
| Reactant | 2-Fluoroisonicotinic acid | HCID 345360 | — |
| Product | 3-[(2-Methyl-4-iodophenyl)amino]isonicotinic acid | HCID 57649617 | — |
Reaction Steps
Synthesized as intermediate 1 by reacting 4.7 mmol of 2-methyl-4-iodoaniline with 7.0 mmol 2-fluoroisonicotinic acid. LC/MS [(5.3 min; 355 (M+1)]. See detailed procedure in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524911B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-dda7e1a6441c464495e16a54afe3c0a0 |
| Source note | uspto-grants-2013_09 |