HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 39508Generated: October 24, 2026
Hydrogen Peroxide → 3-Fluoroisonicotinic acid 1-oxide
https://huagongshe.com/en/reaction/39508
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Fluoroisonicotinic acid 1-oxide | HCID 57649637 | — |
Reaction Steps
To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08524911B2 |
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| Source dataset | uspto-grants-2013_09 |
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| ORD ID | ord-eefb4f777a6c4d60abf2477d1e1f9e78 |
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| Source note | uspto-grants-2013_09 |
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