2,2-Bis(trifluoromethyl)decanoyl fluoride → Sodium 2,2-bis(trifluoromethyl)decanoate

Participants

Reaction Steps

The procedure of Example 1 was followed using 2,2-bis(trifluoromethyl)decanoyl fluoride (6.11 g, 19.7 mmol), sodium trimethylsilanolate (2.21 g, 19.7 mmol) and dry ether (20 mL). The product, sodium 2,2-bis(trifluoromethyl)decanoate, was isolated as a waxy solid (5.5 g, 85% yield) by concentrating the filtrate under vacuum: 1H NMR (CDCl3) δ 0.88 (m, CH3, 3H), 1.30 (m, CH2, 12H), 2.10 ppm (m, CH2, 2H); 19F NMR (D2O/acetone) δ -62.0 ppm (brs, CF3,6F). Anal. Calcd. for C12H17F6NaO2 : C, 43.64; H, 5.19; F, 34.52. Found: C, 44.34; H, 5.10; F, 35.58.

Provenance & Evidence