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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 39539Generated: October 23, 2026

N-(2-Aminoethyl)piperidine → 3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamide

https://huagongshe.com/en/reaction/39539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Aminoethyl)piperidineHCID 33944—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamideHCID 11518392—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 2.5 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 4.0 mmol of 2-piperidin-1-ylethylamine. LC/MS [5.40 min; 469 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524911B2
Source datasetuspto-grants-2013_09
ORD IDord-40d5dff0e369493e944fe158bf89f750
Source noteuspto-grants-2013_09