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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395539Generated: October 24, 2026

4-Bromoaniline → Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate

https://huagongshe.com/en/reaction/395539

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromoanilineHCID 7807—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ProductTert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylateHCID 11210451—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-bromoaniline (4.11 g) was treated in the same manner as described in Example 37 to give white crystalline powder of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605620B1
Source datasetuspto-grants-2003_08
ORD IDord-18d1678cdb374b6abdb01b8c6abfb1c9
Source noteuspto-grants-2003_08