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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 39593Generated: October 23, 2026

3-(Aminomethyl)phenol → 3-[(2-fluoro-4-iodophenyl)amino]-N-(3-hydroxybenzyl)isonicotinamide

https://huagongshe.com/en/reaction/39593

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Aminomethyl)phenolHCID 735894—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-(3-hydroxybenzyl)isonicotinamideHCID 11503611—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-(3-hydroxybenzyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.22 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.35 mmol of 3-hydroxybenzylamine. LC/MS [6.01 min; 464 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524911B2
Source datasetuspto-grants-2013_09
ORD IDord-7f756c64875e4f958c08287c31129f23
Source noteuspto-grants-2013_09